{"id":16293,"date":"2025-06-24T16:32:42","date_gmt":"2025-06-24T14:32:42","guid":{"rendered":"https:\/\/ethosherbals.com\/?post_type=product&p=16293"},"modified":"2025-06-25T17:02:52","modified_gmt":"2025-06-25T15:02:52","slug":"huperzinea","status":"publish","type":"product","link":"https:\/\/ethosherbals.com\/fr\/shop\/herbs-for-the-spirit\/creativity\/huperzinea\/","title":{"rendered":"Huperzine A 1%"},"content":{"rendered":"

Huperzine A is a naturally occurring compound extracted from Chinese club moss (Huperzia serrata<\/em>), traditionally used to support cognitive function. Known for its ability to enhance memory, focus, and mental clarity, it works by inhibiting acetylcholinesterase\u2014an enzyme that breaks down acetylcholine, a key neurotransmitter for learning and attention.<\/p>\n

i) Primary Pharmacological Actions of Huperzine A:<\/strong><\/h3>\n

Pharmacological Actions of Huperzine A<\/strong><\/h2>\n

\ud83d\udd39 Acetylcholine System \u2013 Indirect Agonism<\/strong><\/h3>\n
    \n
  • \n

    Primary mechanism<\/strong>: Potent, reversible inhibitor of acetylcholinesterase (AChE)<\/strong><\/p>\n<\/li>\n

  • \n

    By inhibiting AChE, it prevents the breakdown of acetylcholine (ACh)<\/strong>, leading to increased levels of ACh in the synaptic cleft.<\/p>\n<\/li>\n

  • \n

    This produces pro-cholinergic effects<\/strong>, enhancing memory, learning, and focus.<\/p>\n<\/li>\n

  • \n

    It is considered an indirect cholinergic agonist<\/strong> via this mechanism.<\/p>\n<\/li>\n<\/ul>\n

    \n

    \ud83d\udd39 NMDA Receptor Modulation<\/strong><\/h3>\n
      \n
    • \n

      Huperzine A also acts as a non-competitive NMDA receptor antagonist<\/strong>.<\/p>\n<\/li>\n

    • \n

      This may protect neurons from glutamate-induced excitotoxicity, contributing to its neuroprotective<\/strong> effects.<\/p>\n<\/li>\n<\/ul>\n

      \n

      \ud83d\udd39 Neuroprotective & Antioxidant Effects<\/strong><\/h3>\n
        \n
      • \n

        Antioxidant activity<\/strong>: Scavenges free radicals and reduces oxidative stress.<\/p>\n<\/li>\n

      • \n

        Mitochondrial protection<\/strong>: May preserve mitochondrial function under oxidative load.<\/p>\n<\/li>\n

      • \n

        Anti-apoptotic effects<\/strong>: Shown in some models to reduce cell death in neurodegenerative conditions.<\/p>\n<\/li>\n<\/ul>\n

        \n

        \ud83d\udd39 Anti-inflammatory and Blood-Brain Barrier Penetration<\/strong><\/h3>\n
          \n
        • \n

          Crosses the blood-brain barrier<\/strong> efficiently.<\/p>\n<\/li>\n

        • \n

          May reduce inflammation in neural tissue via modulation of inflammatory pathways.<\/p>\n<\/li>\n<\/ul>\n

          \n

          Summary Table<\/h2>\n
          \n
          \n\n\n\n\n\n\n\n\n
          Action Type<\/th>\nTarget<\/th>\nEffect<\/th>\n<\/tr>\n<\/thead>\n
          Enzyme Inhibition<\/td>\nAcetylcholinesterase (AChE)<\/td>\n\u2191 Acetylcholine<\/td>\n<\/tr>\n
          Receptor Modulation<\/td>\nNMDA receptor (antagonist)<\/td>\n\u2193 Excitotoxicity<\/td>\n<\/tr>\n
          Antioxidant<\/td>\nFree radicals \/ ROS<\/td>\n\u2193 Oxidative stress<\/td>\n<\/tr>\n
          Neuroprotection<\/td>\nMitochondria, apoptosis paths<\/td>\n\u2191 Cell survival<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n

          \ud83d\udccf Typical Dosage Guidelines<\/strong><\/h3>\n
          \n
          \n\n\n\n\n\n\n\n
          Use Case<\/th>\nDose Range<\/th>\nFrequency<\/th>\n<\/tr>\n<\/thead>\n
          Cognitive Support<\/strong><\/td>\n5\u201310 mg Of 1% Powder<\/td>\n1\u20132\u00d7 daily<\/td>\n<\/tr>\n
          Nootropic Use<\/strong><\/td>\n10-20 mg Of 1% Powder<\/td>\n1\u00d7 daily or cyclic<\/td>\n<\/tr>\n
          Neurodegeneration (clinical research)<\/strong><\/td>\nUp to 40 mg\/day of 1% Powder<\/td>\nUnder supervision<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
          \n
          <\/div>\n<\/div>\n<\/div>\n<\/div>\n
          \n

          \u2705 Microgram<\/em> (mcg) doses \u2013 very potent compound
          \u26a0\ufe0f Tolerance and saturation may occur with daily use<\/p>\n<\/blockquote>\n

          \n

          \ud83d\udd04 Cycling Guidelines<\/strong><\/h3>\n
            \n
          • \n

            On-cycle<\/strong>: 2\u20134 weeks on<\/p>\n<\/li>\n

          • \n

            Off-cycle<\/strong>: 1\u20132 weeks off<\/p>\n<\/li>\n

          • \n

            This helps prevent receptor downregulation and preserve effectiveness.<\/p>\n<\/li>\n<\/ul>\n

            \n

            \u23f1\ufe0f Pharmacokinetics<\/strong><\/h3>\n
              \n
            • \n

              Half-life<\/strong>: ~10\u201314 hours<\/p>\n<\/li>\n

            • \n

              Onset<\/strong>: ~30\u201360 minutes<\/p>\n<\/li>\n

            • \n

              Duration<\/strong>: Up to 24 hours<\/p>\n<\/li>\n<\/ul>\n

              \n

              \u26a0\ufe0f Important Notes<\/strong><\/h3>\n
                \n
              • \n

                Do not exceed 200 mcg per dose<\/strong> without medical guidance<\/p>\n<\/li>\n

              • \n

                May cause vivid dreams<\/strong>, nausea<\/strong>, or headaches<\/strong> in sensitive individuals<\/p>\n<\/li>\n

              • \n

                Avoid combining<\/strong> with other strong cholinergics without monitoring<\/p>\n<\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"

                Note:<\/strong> For research and educational purposes only. Not intended for human consumption.<\/p>","protected":false},"featured_media":16307,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[2108,112,1223,266,261,263,1225,1086],"product_tag":[2191,2278,199,2279],"class_list":{"0":"post-16293","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-nootropics","7":"product_cat-smartshop","8":"product_cat-pain-inflammation","9":"product_cat-effects-locator","10":"product_cat-creativity","11":"product_cat-lucid_dreams","12":"product_cat-memory-enhancement","13":"product_cat-mental-focus","14":"product_tag-focus","15":"product_tag-huperzine-a","16":"product_tag-nootropic","17":"product_tag-potent-cholinergic","19":"first","20":"instock","21":"taxable","22":"shipping-taxable","23":"purchasable","24":"product-type-variable"},"yoast_head":"\nHuperzine A 1% - Ethos Herbals<\/title>\n<meta name=\"description\" content=\"Note: For research and educational purposes only. Not intended for human consumption.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ethosherbals.com\/fr\/shop\/herbs-for-the-spirit\/creativity\/huperzinea\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Huperzine A 1% - Ethos Herbals\" \/>\n<meta property=\"og:description\" content=\"Note: For research and educational purposes only. Not intended for human consumption.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ethosherbals.com\/fr\/shop\/herbs-for-the-spirit\/creativity\/huperzinea\/\" \/>\n<meta property=\"og:site_name\" content=\"Ethos Herbals\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ethos.herbals\" \/>\n<meta property=\"article:modified_time\" content=\"2025-06-25T15:02:52+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ethosherbals.com\/wp-content\/uploads\/2025\/06\/huperzine.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ethosherbals.com\\\/shop\\\/herbs-for-the-spirit\\\/creativity\\\/huperzinea\\\/\",\"url\":\"https:\\\/\\\/ethosherbals.com\\\/shop\\\/herbs-for-the-spirit\\\/creativity\\\/huperzinea\\\/\",\"name\":\"Huperzine A 1% - Ethos Herbals\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ethosherbals.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/ethosherbals.com\\\/shop\\\/herbs-for-the-spirit\\\/creativity\\\/huperzinea\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/ethosherbals.com\\\/shop\\\/herbs-for-the-spirit\\\/creativity\\\/huperzinea\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ethosherbals.com\\\/wp-content\\\/uploads\\\/2025\\\/06\\\/huperzine.jpg\",\"datePublished\":\"2025-06-24T14:32:42+00:00\",\"dateModified\":\"2025-06-25T15:02:52+00:00\",\"description\":\"Note: For research and educational purposes only. Not intended for human consumption.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/ethosherbals.com\\\/shop\\\/herbs-for-the-spirit\\\/creativity\\\/huperzinea\\\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/ethosherbals.com\\\/shop\\\/herbs-for-the-spirit\\\/creativity\\\/huperzinea\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\\\/\\\/ethosherbals.com\\\/shop\\\/herbs-for-the-spirit\\\/creativity\\\/huperzinea\\\/#primaryimage\",\"url\":\"https:\\\/\\\/ethosherbals.com\\\/wp-content\\\/uploads\\\/2025\\\/06\\\/huperzine.jpg\",\"contentUrl\":\"https:\\\/\\\/ethosherbals.com\\\/wp-content\\\/uploads\\\/2025\\\/06\\\/huperzine.jpg\",\"width\":1024,\"height\":1024},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/ethosherbals.com\\\/shop\\\/herbs-for-the-spirit\\\/creativity\\\/huperzinea\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u0391\u03c1\u03c7\u03b9\u03ba\u03ae\",\"item\":\"https:\\\/\\\/ethosherbals.com\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Shop\",\"item\":\"https:\\\/\\\/ethosherbals.com\\\/shop\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Huperzine A 1%\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/ethosherbals.com\\\/#website\",\"url\":\"https:\\\/\\\/ethosherbals.com\\\/\",\"name\":\"Ethos Herbals\",\"description\":\"enhance your potential\",\"publisher\":{\"@id\":\"https:\\\/\\\/ethosherbals.com\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/ethosherbals.com\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/ethosherbals.com\\\/#organization\",\"name\":\"Ethos Herbals\",\"url\":\"https:\\\/\\\/ethosherbals.com\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\\\/\\\/ethosherbals.com\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"http:\\\/\\\/ethosherbals.com\\\/wp-content\\\/uploads\\\/2022\\\/02\\\/Complete-logotype-Black@2x.png\",\"contentUrl\":\"http:\\\/\\\/ethosherbals.com\\\/wp-content\\\/uploads\\\/2022\\\/02\\\/Complete-logotype-Black@2x.png\",\"width\":1187,\"height\":322,\"caption\":\"Ethos Herbals\"},\"image\":{\"@id\":\"https:\\\/\\\/ethosherbals.com\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/ethos.herbals\",\"https:\\\/\\\/www.instagram.com\\\/ethos.herbals\\\/\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Huperzine A 1% - Ethos Herbals","description":"Note: For research and educational purposes only. Not intended for human consumption.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/ethosherbals.com\/fr\/shop\/herbs-for-the-spirit\/creativity\/huperzinea\/","og_locale":"fr_FR","og_type":"article","og_title":"Huperzine A 1% - Ethos Herbals","og_description":"Note: For research and educational purposes only. Not intended for human consumption.","og_url":"https:\/\/ethosherbals.com\/fr\/shop\/herbs-for-the-spirit\/creativity\/huperzinea\/","og_site_name":"Ethos Herbals","article_publisher":"https:\/\/www.facebook.com\/ethos.herbals","article_modified_time":"2025-06-25T15:02:52+00:00","og_image":[{"width":1024,"height":1024,"url":"https:\/\/ethosherbals.com\/wp-content\/uploads\/2025\/06\/huperzine.jpg","type":"image\/jpeg"}],"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/ethosherbals.com\/shop\/herbs-for-the-spirit\/creativity\/huperzinea\/","url":"https:\/\/ethosherbals.com\/shop\/herbs-for-the-spirit\/creativity\/huperzinea\/","name":"Huperzine A 1% - Ethos Herbals","isPartOf":{"@id":"https:\/\/ethosherbals.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/ethosherbals.com\/shop\/herbs-for-the-spirit\/creativity\/huperzinea\/#primaryimage"},"image":{"@id":"https:\/\/ethosherbals.com\/shop\/herbs-for-the-spirit\/creativity\/huperzinea\/#primaryimage"},"thumbnailUrl":"https:\/\/ethosherbals.com\/wp-content\/uploads\/2025\/06\/huperzine.jpg","datePublished":"2025-06-24T14:32:42+00:00","dateModified":"2025-06-25T15:02:52+00:00","description":"Note: For research and educational purposes only. Not intended for human consumption.","breadcrumb":{"@id":"https:\/\/ethosherbals.com\/shop\/herbs-for-the-spirit\/creativity\/huperzinea\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/ethosherbals.com\/shop\/herbs-for-the-spirit\/creativity\/huperzinea\/"]}]},{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/ethosherbals.com\/shop\/herbs-for-the-spirit\/creativity\/huperzinea\/#primaryimage","url":"https:\/\/ethosherbals.com\/wp-content\/uploads\/2025\/06\/huperzine.jpg","contentUrl":"https:\/\/ethosherbals.com\/wp-content\/uploads\/2025\/06\/huperzine.jpg","width":1024,"height":1024},{"@type":"BreadcrumbList","@id":"https:\/\/ethosherbals.com\/shop\/herbs-for-the-spirit\/creativity\/huperzinea\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u0391\u03c1\u03c7\u03b9\u03ba\u03ae","item":"https:\/\/ethosherbals.com\/"},{"@type":"ListItem","position":2,"name":"Shop","item":"https:\/\/ethosherbals.com\/shop\/"},{"@type":"ListItem","position":3,"name":"Huperzine A 1%"}]},{"@type":"WebSite","@id":"https:\/\/ethosherbals.com\/#website","url":"https:\/\/ethosherbals.com\/","name":"Ethos Herbals","description":"enhance your potential","publisher":{"@id":"https:\/\/ethosherbals.com\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/ethosherbals.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"},{"@type":"Organization","@id":"https:\/\/ethosherbals.com\/#organization","name":"Ethos Herbals","url":"https:\/\/ethosherbals.com\/","logo":{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/ethosherbals.com\/#\/schema\/logo\/image\/","url":"http:\/\/ethosherbals.com\/wp-content\/uploads\/2022\/02\/Complete-logotype-Black@2x.png","contentUrl":"http:\/\/ethosherbals.com\/wp-content\/uploads\/2022\/02\/Complete-logotype-Black@2x.png","width":1187,"height":322,"caption":"Ethos Herbals"},"image":{"@id":"https:\/\/ethosherbals.com\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/ethos.herbals","https:\/\/www.instagram.com\/ethos.herbals\/"]}]}},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/ethosherbals.com\/fr\/wp-json\/wp\/v2\/product\/16293","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ethosherbals.com\/fr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/ethosherbals.com\/fr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/ethosherbals.com\/fr\/wp-json\/wp\/v2\/comments?post=16293"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ethosherbals.com\/fr\/wp-json\/wp\/v2\/media\/16307"}],"wp:attachment":[{"href":"https:\/\/ethosherbals.com\/fr\/wp-json\/wp\/v2\/media?parent=16293"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/ethosherbals.com\/fr\/wp-json\/wp\/v2\/product_brand?post=16293"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/ethosherbals.com\/fr\/wp-json\/wp\/v2\/product_cat?post=16293"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/ethosherbals.com\/fr\/wp-json\/wp\/v2\/product_tag?post=16293"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}