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SR-17018

95,00 

Note: For research and educational purposes only. Not intended for human consumption.

Beschreibung

SR-17018 – Precision Dopamine Modulation for Mental Edge

SR-17018 is a next-generation dopamine receptor modulator that has gained attention for its high selectivity and unique mechanism of action. Unlike traditional dopaminergic compounds, SR-17018 targets the mu-opioid receptor (MOR) with biased agonism, meaning it can activate beneficial pathways without triggering the typical side effects associated with opioids. This makes it a subject of interest for researchers studying pain relief, cognitive function, and neuroplasticity. Above everything else though, SR-17018 is being studied for its amazing potential at minimizing withdrawals, even from strong opiate substances!

Preclinical studies suggest that SR-17018 may play a role in:

  • Enhancing dopamine signaling with less tolerance buildup

  • Supporting mood regulation and motivation

  • Offering non-addictive pain modulation potential

  • Promoting neuroadaptation in reward-related brain circuits

Its unique pharmacological profile makes SR-17018 a valuable research tool in the exploration of chronic pain, addiction science, and dopaminergic balance.

Potential Opiate Cessation Protocol with SR-17018 

SR-17018 is an experimental compound with biased agonism at the mu-opioid receptor (MOR) — meaning it selectively activates some pathways (e.g. analgesia) while avoiding others (e.g. respiratory depression, reward). It’s not approved for human use but has shown promise in animal studies for:

  • Reducing opioid tolerance and dependence

  • Producing pain relief without euphoria

  • Minimizing withdrawal symptoms

Because it’s not yet clinically approved, there’s no standardized protocol for quitting opiates with SR-17018. However, based on preclinical data, here’s a hypothetical research-based protocol that some might explore in experimental contexts. Here is a very interesting FAQ from Reddit for minimizing withdrawals with SR-17018:

https://www.reddit.com/r/Opioid_RCs/comments/1hcgmor/sr17018_dosing_guide_for_quitting_opioids/

Zusätzliche Informationen
Συσκευασία

1000 mg.

TECHNICAL SPECIFICATIONS :

TECHNICAL SPECIFICATIONS :

 

Aspect Details
Product Name SR-17018
CAS Number

2134602-45-0

Purity >99%
 

Test Method

COA/Lcms/Nmr/HPLC/UV

Ideal storage is done in refrigerator, in temperatures of 2-8 Celcius. Has to be labeled clearly at all times and be kept out of reach of children!

WHAT TO AVOID :

WHAT TO AVOID :

1. Overuse or Chronic High Doses

  • 5-Amino-1MQ increases NAD⁺ levels and modulates metabolism — great for fat loss and cellular energy.

  • But chronic high-dose use may:

    • Overstimulate metabolic pathways

    • Alter methylation balance (since NNMT is tied to methyl donor cycling)

    • Lead to unintended side effects like fatigue, irritability, or hormonal imbalance

✅ Stick to researched dosing windows (typically 10–20 mg/day for short cycles in animal models)


2. Concurrent Use with Other NNMT Inhibitors or Methylation Modulators

  • Combining with supplements or drugs that also inhibit NNMT or alter methylation (e.g., SAMe, niacin, methylfolate, resveratrol) could lead to:

    • Excess NAD⁺ accumulation

    • Methyl donor depletion

    • Unpredictable metabolic effects

⚠️ Use caution and monitor methylation-related pathways if stacking


3. Use in Hormone-Sensitive or Cancer Conditions

  • NNMT is implicated in tumor metabolism and cancer cell survival in some contexts.

  • While 5-Amino-1MQ may reduce fat cell expansion, it could theoretically affect tumor metabolism, especially in hormone-sensitive tissues.

❌ Avoid use in active cancer, estrogen-sensitive conditions, or without supervision in at-risk populations


4. Poor Storage & Handling

  • 5-Amino-1MQ is light- and moisture-sensitive:

    • Avoid storing in hot, humid, or bright environments

    • Once reconstituted, must be refrigerated and used within 1–2 weeks


⚠️ 5. Use During Pregnancy or Breastfeeding

  • No safety data exists.

  • The metabolic impact and gene expression changes may pose unknown risks during fetal development.

Do not use during pregnancy, breastfeeding, or in children


6. Combining with Fat-Burning Stimulants (without monitoring)

  • Combining with:

    • Yohimbine

    • Clenbuterol

    • High-dose caffeine or ephedrine

…may overactivate fat oxidation and stress pathways, leading to:

  • Jitteriness

  • Adrenal fatigue

  • Sleep disruption

🟡 Use caution when stacking with other metabolic stimulants

DISCLAIMER :

DISCLAIMER :

As stated in the short description, this and other products of subsection of “Nootropics” in our e-shop are NOT intended for human consumption! Those products are available for collection purposes or for other lawful use for which the consumer has taken care to be explicitly informed on a personal level in every aspect that may be affecting them.

The information provided in the descriptions of products which can be found in “Nootropics” subsection – as available from ethosherbals.com, SMARTSHOP Main Category – is of an academic nature. This information is not intended to be used for human consumption of the products in question. It is not intended to diagnose, prevent or treat any medical condition. It is not intended to be a substitute for any medical treatment.


											
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