Magnesium L-Threonate

Magnesium Threonate is a highly bioavailable form of magnesium designed to support cognitive function, memory, and brain health. Ideal for students, professionals, and anyone looking to enhance mental clarity and reduce brain fog. Gentle on the stomach and effective where it counts — the  mind.

i) ✅ Primary Pharmacological Actions of Magnesium Threonate:

✅ Potential Benefits

• Enhances cognitive function – Supports learning, memory, and mental clarity

• Boosts brain magnesium levels – Crosses the blood-brain barrier more effectively than other forms

• May reduce brain fog – Helps improve focus and mental sharpness

• Supports long-term brain health – Promotes synaptic density and neural plasticity

• May improve sleep quality – Helps calm the nervous system and regulate sleep patterns

ii) Magnesium Threonate Primary Pharmacological Properties

• Modulates NMDA receptors (indirectly):
  Magnesium acts as a natural blocker of NMDA receptors, which helps prevent overexcitation (linked to neurotoxicity and cognitive decline).
  → This action helps regulate glutamatergic signaling (excitatory neurotransmission).

• Supports GABAergic function:
  Higher brain magnesium levels may enhance the activity of GABA receptors, contributing to a calming effect and potentially improving sleep and reducing anxiety.

• Influences synaptic plasticity:
  Magnesium is involved in long-term potentiation (LTP), a key process in learning and memory. Studies on Magnesium Threonate show enhanced synaptic density in brain regions like the hippocampus.

iii) Magnesium Threonate Dosing Overview

• Standard dose (adults):
  1,500 mg to 2,000 mg per day of Magnesium L-Threonate split into 2 dosages
• Initital research dosages of 500 mg per day are recommended to gauge the effects.

iv) ⚠️ Important Considerations & Warnings

• Consult a healthcare provider before use if you have a medical condition (especially kidney disease) or are taking medications.

• May cause drowsiness or headaches in some individuals, especially at higher doses.

• Start with a lower dose if you are sensitive or new to magnesium supplements.

• May interact with medications that affect magnesium levels (e.g., diuretics, antibiotics, or heart medications).

• Digestive upset –>  try taking it with food or reduce the dosage.

• Do not exceed the recommended dosage unless directed by a healthcare professional.