Oroxylin A 15,00 45,00 
Επιστροφή στα προϊόντα
Guanfacine 23,00 40,00 

Sunifiram

10,00 17,00 

Note: For research and educational purposes only. Not intended for human consumption.

Περιγραφή

Sunifiram is a powerful nootropic compound known for its cognitive-enhancing properties. Often categorized as an AMPAkine, it is designed to support memory, focus, and learning. Anecdotal reports include heightened mental clarity, increased motivation, and faster information processing.

i) ✅ Primary Pharmacological Actions of Sunifiram:

Potential Benefits

  • AMPA receptor: Positive modulation → improved synaptic transmission

  • Cholinergic system: Enhanced ACh release → improved attention & memory

  • NMDA receptor: Facilitated signaling → support for learning & plasticity

  • Intracellular signaling: Activation of CaMKII & PKC → supports LTP and memory consolidation

ii) Sunifiram Primary Pharmacological Properties

1. AMPA Receptor Agonism / Modulation

  • Sunifiram is not a direct agonist but acts as an AMPA receptor modulator (AMPAkine-like), enhancing glutamatergic transmission.

  • It increases AMPA receptor phosphorylation, which is linked to increased synaptic plasticity and long-term potentiation (LTP)—the cellular basis for learning and memory.

2. Cholinergic System Activation

  • Sunifiram enhances acetylcholine (ACh) release in the cerebral cortex.

  • This action is likely indirect, possibly via NMDA receptor interaction, but it results in improved attention and memory.

3. NMDA Receptor Involvement

  • While not a direct agonist, Sunifiram appears to facilitate NMDA receptor function.

  • This may be due to upregulation of signaling pathways that support NMDA receptor-mediated synaptic plasticity.

iii) 💊 Sunifiram Dosing Overview

Typical Dose Range:
🔹 2–10 mg per dose, taken 1–3 times daily.

Common Starting Point:
🔹 5 mg, taken once daily to assess sensitivity.

Route of Administration:
🔹 Oral (most common)
🔹 Sublingual (faster onset, more bioavailable)

Onset & Duration:

  • Onset: ~15–30 minutes (sublingual may be faster)

  • Duration: 2–4 hours (effects may feel longer due to lingering mental clarity)


Timing & Frequency:

  • Tolerance potential: Some users report rapid tolerance with daily use. To mitigate this, it’s often used cyclically (e.g., 2–3 days on, followed by days off).

With or Without Food?

  • On an empty stomach for faster onset and better absorption.

 


iv) ⚠️ Important Considerations & Warnings

  • Low-dose potency: Sunifiram is highly active at microgram-to-milligram levels, so accurate measuring (preferably with a microgram scale) is essential.

  • Stacking: Sometimes paired with choline sources (e.g., Alpha-GPC, CDP-Choline) to support acetylcholine levels and reduce the risk of headaches.

 

Επιπρόσθετες Πληροφορίες
Συσκευασία

1000 mg.

,

2000 mg.

TECHNICAL SPECIFICATIONS :

TECHNICAL SPECIFICATIONS :

Aspect Details
Product Name
Sunifiram
CAS
314728-85-3
Purity 99%
Test Method HPLC

 

Ideal storage is done in a cool and dry place, away from direct sunlight and heat. Has to be labeled clearly at all times and be kept out of reach of children!

WHAT TO AVOID :

WHAT TO AVOID :

DISCLAIMER :

DISCLAIMER :

As stated in the short description, this and other products of subsection of
“Nootropics” in our e-shop are NOT intended for human consumption! Those products are available for collection purposes or for other lawful use for which the consumer has taken care to be explicitly informed on a personal level in every aspect that may be affecting them.

The information provided in the descriptions of products which can be found into “Nootropics” subsection – as available from ethosherbals.com, SMARTSHOP Main Category– is of an academic nature. This information is not intended to be used for human consumption of the products in question. It is not intended to diagnose, prevent or treat any medical condition. It is not intended to be a substitute for any medical treatment.


											
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